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  • 1
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    ISSN: 1600-0714
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract Twelve cases of oral leukoplakia were studied at the light and electron microscopic levels. In clinical leukoplakia simplex and verrucosa, both light and electron microscopic investigations revealed evidence of increased keratinization. Clinically erosive and histologically dysplastic leukoplakias showed ultrastructural alterations characteristic of oral carcinomas in some instances.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    ISSN: 1600-0714
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    ISSN: 1600-0714
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract. Stensen's duct was ligated in 18 mature Sprague-Dawley rats and the parotid gland was examined at intervals of up to 90 days. Standard preparatory techniques were used for light and electron microscopy. Parotid tissue decreases with time following ligation of the duct. The course from 1 week onward is one of progressive atrophy; at 3 months the number of identifiable acini is greatly decreased. The controls remained unchanged throughout the course of the study. Ligation of the parotid duct will produce glandular atrophy. The clinical implications are that for some parotid conditions ligation may be an effective treatment which avoids the hazards of parotid surgery.
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  • 4
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    ISSN: 1600-0714
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract. Some of the clinical and histological features of 12 retention and 224 extravasation mucoceles of minor oral salivary glands are compared. Retention mucoceles occurred in a much older age group than extravasation mucoceles, and were very uncommon in the lower lip which was by far the most frequent site for extravasation mucoceles. All the retention mucoceles were lined by eosinophilic, oncocyte-like epithelium as either a double or a single layer of columnar, cuboidal or compressed flat cells. There is no evidence to support the generally accepted suggestion that retention mucoceles are due to duct blockage, and it is postulated that either they may arise as spontaneous cystic change in an oncocyte-lined duct, or they represent a cystic type of papillary cystadenoma.
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  • 5
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    ISSN: 1600-0714
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1600-0714
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract. Insoluble collagen was prepared from gingivae of full term, stillborn infants (SI) and from that of patients exhibiting gingival hyperplasia that was secondary to diphenylhydantoin therapy (DPH). During the preparations only 4 % of the collagen from DPH was extracted and 17 % from SI gingivae was solubilized, by neutral salt and dilute acid extractants. Subsequent amino acid analysis indicated the presence of a relatively large quantity of the noncollagenous protein(s) in the DPH collagen preparation. After collagen samples were converted to soluble cyanogen bromide (CNBr) pep-tides, the noncollagenous protein(s) proved to be insoluble in the dilute citrate buffer routinely used for initial chromotographic separation of the CNBr peptides. This fraction, whether from DPH or SI gingivae, had essentially the same composition. The noncollagenous protein fraction comprised about 7 and 20 %, respectively, of the dry weights of the SI and DPH insoluble collagen preparations.CNBr peptides from gingival collagen have been purified and shown to be identical with those reported for human skin collagen. Thus, the collagen of gingivae is principally of the type with the chain structure [αl(I)]2α2. Preliminary data strongly suggest the presence in gingivae of a lower level of collagen of the [al (III)]s type.
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  • 7
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    ISSN: 1600-0714
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract. Histopathological studies were conducted on experimental carcinogenesis in mouse salivary glands using D L-isoproterenol hydochloride (isoproterenol) and 9 10-dimethyl-1 2-benzantliracene (DMBA). DM BA was admisistered once at 1 mg/0.02 ml in olive oil to the salivary glands, and isoproterenol was injected intraperitoneally at 1 mg/0.05 ml saline solution three times a week for 2 weeks al different periods during the oncogenic process. Salivary glands treated with carcinogen showed a relatively constant sequence of changes and developed epithelial and mesenchymal tumors irrespective of isoproterenol administration. Isoproterenol did not influence the development of another type of tumor; however, it did retard the oncogenic processes.
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  • 8
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    ISSN: 1600-0714
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Book reviews in this article: Principles and Techniques of Scanning Electron Microscopy: Biological Applications, Vol, 6, ed. Hayat, M. A.
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  • 9
    ISSN: 1600-0714
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract. X-ray diffraction and electron spin resonance (ESR) analyses were conducted on calcifying epithelial odontogenic tumor (CEOT) associated with abundant calcification in order to compare its mineral structure with that of surrounding cortical bone. The material under investigation was removed from the canine-premolar region of the left maxilla of a 39-year-old woman. The principal findings were that the mineral phase of CEOT consists of apatite crystals and that the crystallinity of the crystals is higher than that of bone apatite. ESR spectra of CEOT are similar to those of bone sample. Quantitative ESR analysis indicates that CEOT shows a higher crystallinity coefficient – defined by Ostrowski et al. (1972, 1974) as the ratio of spin concentration to the ash content of the sample – than bone. Based on the data, it can be concluded that the calcification in CEOT has a higher crystalline structure than the cortical bone.
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  • 10
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    ISSN: 1600-0714
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract. The oral findings in two Peruvian brothers, 10- and 11-years-old, with acatalasia are presented. Gingival necrosis and severe alveolar bone destruction were the main oral manifestations. Otherwise the patients were in good health. Thirteen hypocatalasemic individuals, including both parents, were found among 29 relatives of the probands examined from four generations. No other acatalasemic individuals were found. Hypocatalectic relatives of the probands did not have oral lesions, and no other abnormalities were detected. The parents of the affected children were not known to be related; however, both parents and their families come from the same small rural community. The inheritance pattern in the kindred was compatible with an autosomal recessive disorder. It is postulated that the gingival lesions resulted from damage to tissue from hydrogen peroxide generated by organisms in gingival plaque. The hydrogen peroxide cannot be degraded by gingival tissue or by leukocytes genetically lacking the enzyme catalase.
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