Publication Date:
2018-07-12
Description:
An in vitro paradigm to assess potential anti-Aβ antibodies for Alzheimer’s disease An in vitro paradigm to assess potential anti-Aβ antibodies for Alzheimer’s disease, Published online: 11 July 2018; doi:10.1038/s41467-018-05068-w The optimal Aβ species to target for the potential treatment of Alzheimer’s disease has not yet been established. Here, the authors describe an in vitro assay that uses extracts from brain tissue from patients with Alzheimer’s disease, and application to human iPSC-derived neurons, to compare the neuroprotective potential of several anti-Aβ antibodies.
Electronic ISSN:
2041-1723
Topics:
Biology
,
Chemistry and Pharmacology
,
Natural Sciences in General
,
Physics
