Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    Keywords: OPTIMIZATION ; SIMULATIONS ; radiotherapy ; Germany ; PROSTATE ; THERAPY ; imaging ; SYSTEM ; RISK ; radiation ; SIMULATION ; TARGET ; DISTRIBUTIONS ; RADIATION-THERAPY ; DESIGN ; ENERGY ; HEAD ; IMRT ; FEASIBILITY ; THERAPIES ; DOSE DISTRIBUTIONS ; radiation therapy ; BEAMS ; Protons ; SPREAD ; INVESTIGATE ; COVERAGE ; PARTICLE SELECTION ; PHOTON IMRT
    Abstract: In recent experiments, quasi-monoenergetic and well-collimated very-high energy electron (VHEE) beams were obtained by laser-plasma accelerators. We investigate their potential use for radiation therapy. Monte Carlo simulations are used to study the influence of the experimental characteristics such as beam energy, energy spread and initial angular distribution on the dose distributions. It is found that magnetic focusing of the electron beam improves the lateral penumbra. The dosimetric properties of the laser-accelerated VHEE beams are implemented in our inverse treatment planning system for intensity-modulated treatments. The influence of the beam characteristics on the quality of a prostate treatment plan is evaluated. In comparison to a clinically approved 6MV IMRT photon plan, a better target coverage is achieved. The quality of the sparing of organs at risk is found to be dependent on the depth. The bladder and rectum are better protected due to the sharp lateral penumbra at low depths, whereas the femoral heads receive a larger dose because of the large scattering amplitude at larger depths
    Type of Publication: Journal article published
    PubMed ID: 19430107
    Signatur Availability
    BibTip Others were also interested in ...
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...