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  • 1
    ISSN: 1573-7276
    Keywords: human ; hematogenous ; metastatic patterns
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: An attempt is made to clarify some general concepts of hematogenous metastatic patterns in humans, by the use of autopsy data. The significance and problems associated with ‘false negative’ reports are assessed. By the use of metastatic efficiency indices in which the incidence of specific target organ involvement is related to organ blood-flow, ‘seed-and-soil’ effects are discriminated from the effects of differential cancer cell delivery. An analysis of autopsy data from cases with a history of colorectal carcinoma is used to illustrate the importance of metastasis from metastases in the genesis of hematogenous metastatic patterns in humans.
    Type of Medium: Electronic Resource
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