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  • 1
    ISSN: 1573-9686
    Keywords: Respiratory ; Computational model ; Lungs
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Technology
    Notes: Abstract An anatomically accurate model of the conducting airways is essential for adequately simulating gas mixing, particle deposition, heat and water transfer, and fluid distribution. We have extended a two-dimensional tree-growing algorithm to three dimensions for generation of a host-shape dependent three-dimensional conducting airway model. Terminal branches in the model are both length limited and volume-supplied limited. A limit is imposed on the maximum possible branch angle between a daughter and parent branch. Comparison of the resulting model with morphometric data shows that the algorithm produces branching and length ratios, path lengths, numbers of branches, and branching angles very close to those from the experimental data. The correlation between statistics from the generated model and those from morphometric studies suggests that the conducting airway structure can be described adequately using a “supply and demand” algorithm. The resulting model is a computational mesh that can be used for simulating transport phenomena. © 2000 Biomedical Engineering Society. PAC00: 8719Uv, 8710+e
    Type of Medium: Electronic Resource
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