Springer Online Journal Archives 1860-2000
Summary The arcuate nucleus of untreated (control) and castrated adult mice was studied with the electron microscope. Nucleolus-like bodies (NLB) were found in the cytoplasm and occasionally in the dendrites of arcuate neurons. NLB were spherical or ovoid, 0.7–1.5µm in diameter; they were composed of granules 100–150 Å and 200 Å in diameter, and filaments ∼70 Å in diameter. NLB were frequently associated with free ribosomes and cisternae of the rough endoplasmic reticulum. Light microscopic studies with basic dyes and enzymatic digestions showed that these bodies contained some RNA. There was no significant change in the number of NLB in castrated animals.
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